Yes, a 2.2 GPA is a difficult sell when it comes to getting into any MBA program. I don't know a lot about distance learning, but I do believe there is a bit more flexibility with these than in traditional programs. For example, Florida State's distance learning website says that

"In general, we require a 3.0 undergraduate, upper division GPA. Some exceptions/considerations may be given depending upon the undergraduate program, work experience, high GMAT scores, etc."

That seems to be the standard across the board - they look for a 3.0 but exceptions are made.

If it's true that your grades don't say much about your ability - when applying, definitely emphasize work experience. A high GMAT score would seem to me to be essential to your chances here.

A few other schools to look into which have solid distance learning progams:

ASU Carey
Suffolk/Sawyer
Thunderbird

Ralph got a point there, with GPA 2.2 you will need something more to give.
Maybe you can :
1) Create own company (small one) with couple of friends
Then you'll have something that is unique.
2) Proactive volunteering in your community
3) Extensive working experience in multiple countries

When you think about it, there are so many things you can do to enhance
your chance to get accepted at great business school.

Being a dropout is worse than someone with a low GPA,
And yet Steve jobs can make it,...

GPA is only one piece of three, the other two being work experience and GMAT score. Your GPA is something you can't change, so I'd work on the other two. Or, if they're already impressive, then you should be fine.

Out of curiosity, why are you looking at programs only in English-speaking countries? There are English language programs all over the world.